Prosthetic limbs, like this one, might one day be as lifelike as the real thing. Photo: Sgt. Ray Lewis/Bouhammer.com
A replacement limb that moves, feels and responds just like flesh and blood. It’s the holy grail of prosthetics research. The Pentagon’s invested millions to make it happen. But it’s been elusive — until, quite possibly, now.
The body’s own nerves are arguably the biggest barrier towards turning the dream of lifelike replacements into a reality. Peripheral nerves, severed by amputation, can no longer transmit or receive any of the myriad sensory signals we rely on every day. Trying to fuse them with robot limbs, to create a direct neural-prosthetic interface, is no easy task.
But now a team of scientists believe they’ve overcome that massive barrier. Their research is still in the early stages. But if successful, it’d yield artificial arms and legs that can move with agility; discern hot from lukewarm from freezing; and restore even the subtlest sensations of touch.
“We think the interface problem is key to enabling the neuro-prosthetic concept,” Dr. Shawn Dirk, one of the researchers behind the finding, tells Danger Room. “And solving that is how we’re going to give amputees their bodies back.”
Dirk, alongside colleagues at Sandia National Laboratories, the University of New Mexico and the MD Anderson Cancer Center, set out to develop a synthetic substance that could act as a scaffold — that is, an artificial structure that can support tissue growth — successfully merging severed nerves with robotic limbs.
Of course, researchers have already made plenty of efforts to directly integrate nerves and prosthetics. But, according to Dirk, they typically “didn’t use technology that was compatible with nerve fibers,” which are tightly bundled and flexible. “Nerves need to grow and move around; they’re not going to integrate well with a stiff interface.”
Yes, the material comprising the scaffold had to be flexible and fluid, but it also needed to be extremely conductive. Nerve signals are highly localized, and also very, very subtle. An effective neural-prosthetic interface would need to transmit thousands of different signals per second to mimic the behavior of a real limb and its relationship to the brain and body.
To create that ideal interface, Dirk and his colleagues developed their own biocompatible polymers, meant to mimic the properties of nerve tissue. The material is also porous, so that nerves can extend through it, and lined with electrodes, to vastly enhance conductivity.
When surgeons placed the scaffolds onto the severed leg nerves of rats, it didn’t take long before the rats’ own nerve fibers started to grow through the scaffold and fuse back together. Even better, the synthetic material wasn’t rejected by the rats’ immune systems.
“There was a very limited inflammatory response,” Dirk says. “That’s important, because we’re looking for an interface that won’t be rejected by the body. We want something that can last years, decades, and hopefully entire lifetimes.”
The finding marks a huge, huge improvement over previous research efforts. Even Darpa, the Pentagon’s far-out research arm and a leader in prosthetic science, couldn’t seem to figure out a direct neural-prosthetic interface that was adequately sensitive and had a lifespan longer than a few months. In 2010, the agency asked for new research proposals that’d solve both those problems.
And while new prototype prosthetics have some incredible abilities, none of them include a direct interface. In fact, they’ve been designed to avoid one altogether. One Pentagon-funded project used “targeted muscle reinnervation surgery” to develop prosthetics that transmit signals from a bundle of nerves in the chest. Another, led by Johns Hopkins scientists, uses brain-implanted micro-arrays to transmit cues to an artificial limb.
A direct neural-prosthetic interface still remains years away. But if this polymer holds up in subsequent tests, it’ll mean prosthetics far more lifelike than even the most impressive artificial limbs currently in development. Most importantly, in the words of Darpa, prosthetics hooked right into the nervous system “would incorporate the [artificial] limb into the sense-of-self.”
Whole Foods plans to test a Kinect-powered shopping cart that will follow you through stores, track what food you put in the cart and talk to you, Geekwire reports.
The motorized prototype can remember your shopping list, remove items from it as you place them in the cart and even lets you check out and pay when you're done.
The cart is one of hundreds of new Kinect retail and commercial applications being rolled for the Windows version of the device that got its start on the Xbox 360.
Wolfram|Alpha is more than a search engine. It gives you access to the world's facts and data and calculates answers across a range of topics, including science, nutrition, history, geography, engineering, mathematics, linguistics, sports, finance, music...
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A project 7 months in the making. All miniatures 100% handcrafted. For http://www.bamboosushipdx.com. Set Design and Visuals by Lori Nix & Kathleen Gerber [http://www.lorinix.net] Narrated by Jim Donaldson Executive produced, written, edited by Joe Sabia [http://www.joesabia.co] Directed and photographed by Vincent Peone [http://vincentpeone.tumblr.com] Original Score by Michael Thurber [http://www.michaelt.org] w/ AJ Nilles on strings Sound Design, Music Recording/Mixing by Matt McCorkle [http://www.equalsonics.com] Assistant Camera Andrew Brinkman Gaffer Cory Fontana Color by Gloo Studios and Prime Focus NYC
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Video mash-up created by Patrick Peris http://www.facebook.com/patrick.peris.film www.patrickperis.com Twitter @PatPeris Songs (chronological) Don't let me be misunderstood_Santa Esmeralda Counting bodies like sheep to the rhythm of the war drums _ A perfect Circle Clips (in order of appearance) A clockword orange Dirty Harry Kill Bill Vol.1 The Dark Knight Once upon a time in the West Fight Club The Karate Kid Game of Death Smokin' Aces Seven Pulp Fiction Reservoir Dogs Watchmen 300 Crouching Tiger Hidden Dragon Kick-Ass Domino The Good, the Bad and the Ugly Desperado Goodfellas Animatrix Terminator 2 True Romance Robocop Matrix Sucker Punch 2001 A Space Odyssey The Girl with the Dragon Tattoo Million Dollar Baby Limitless Snatch Sherlock Holmes Matrix Revolutions Enter the Dragon The Incredible Hulk Transformers 3 Sin City Immortals Gladiator Tron Legacy Die Hard Dr Strangelove Matrix Reloaded Independance Day Swordfish The Hurt Locker Top Gun Die Hard 2 True Lies For entertainment purposes only, go watch the films again and buy the music.
Each Fire Pit is a high quality, hand cut and crafted fire pit designed for years of heavy use. Rick Wittrig designs each Fire Pit from one quarter inch (6.35 mm) thick carbon steel. They have an iron oxide finish/patina on the outside which will darken a little with time then become permanent. The interior is coated with a high temperature resistant paint and has an 1-1/2" rain drain in the bottom. This high quality fire pit requires no maintenance.
We're talking pretty big numbers here... And an interesting idea about what it'd be like traveling in a Googolplex-sized Universe! With Antonio (Tony) Padill...
The AF2011-A1 Double Barrel Pistol comes actually as the very first industrial double barrel semiautomatic pistol of all times. The original idea came about ...
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This video is a collaboration between Sheldon Neill and Colin Delehanty. All timelapses were shot on the Canon 5D Mark II with a variety of Canon L and Zeiss CP.2 Lenses. Project Yosemite Website: http://projectyose.com Contact info: info@projectyose.com Thanks to Dynamic Perception for their motion controlled dolly and continued support! Dynamic Perception Website: http://dynamicperception.com Track: Outro Album: Hurry Up, We're Dreaming Artist: M83 Site: http://ilovem83.com Publishing: http://emimusicpub.com Licensing: http://bankrobbermusic.com This whole project has been an amazing experience. The two of us became friends through Vimeo and explored a shared interest in timelapsing Yosemite National Park over an extended period of time. We'd like to expand this idea to other locations and would appreciate any suggestions for a future project. Project Yosemite will have an in-depth interview as a main story featured on Yosemite National Park's Spring Newsletter. Sign-Up for a copy here: http://bit.ly/wnfUr9 To view this in 2K, visit: http://youtu.be/OwFbjJasW3E Be sure to change the quality settings to 'Original'. Twitter: https://twitter.com/#!/SheldonNeill https://twitter.com/#!/delehanty Facebook: http://www.facebook.com/sheldon.neill http://www.facebook.com/delehanty Behind The Scenes: http://vimeo.com/35223326 By Dalton Runberg Our hearts go out to the families of Markus Praxmarer who lost his life while climbing Half Dome on September 19th, 2011 and Ranger Ryan Hiller, who was crushed by a tree January 22nd 2012. They will be missed. (A photo of Ranger Ryan Hiller can be found to the right, above the statistics counter)